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KMID : 1039420150490010013
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Journal of Pathology and Translational Medicine
2015 Volume.49 No. 1 p.13 ~ p.22
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Genomic Landscapes of Pancreatic Neoplasia
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Wood Laura D.
Hruban Ralph H.
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Abstract
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Pancreatic cancer is a deadly disease with a dismal prognosis. However, recent advances in sequencing and bioinformatic technology have led to the systematic characterization of the genomes of all major tumor types in the pancreas. This characterization has revealed the unique genomic landscape of each tumor type. This knowledge will pave the way for improved diagnostic and therapeutic approaches to pancreatic tumors that take advantage of the genetic alterations in these neoplasms.
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KEYWORD
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Pancreatic neoplasms, Cancer genomics, Cancer mutation
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